iRucaparib-AP6

Overview

iRucaparib-AP6 is a highly efficient and specific PROTAC PARP1 degrader. iRucaparib-AP6, a non-trapping PARP1 degrader , blocks both the catalytic activity and scaffolding effects of PARP1 . (Pink: PARP-1 ligand ( HY-10617A ); Blue: Cereblon ligand ( HY-10984 ); Black: linker).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > PARP

Product Information

• Catalog No.: HY-130644
• CAS No.: 2410557-00-3
• Molecular Formula: C46H55FN6O11
• Molecular Weight: 886.96
• Purity: 99.03%
• Storage: -20°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
• Solubility: ≥ 2.5 mg/mL (2.82 mM); Clear solution
• Availability: In-stock

Source

Original product source