5-Dehydroepisterol

Overview

5-Dehydroepisterol is a C28 alkylated sterol based on ergostane, and serves as a major component of the sterol pool in Leishmania parasites . The content of 5-Dehydroepisterol in Leishmania promastigotes can be depleted by 22,26-Azasterol, Amiodarone ( HY-14187 ) and Tomatine ( HY-N2166 ). Among these agents, Amiodarone ( HY-14187 ) inhibits the biosynthetic process of this sterol by disrupting the function of squalene epoxidase. 5-Dehydroepisterol can be used in the research of leishmaniasis and cutaneous leishmaniasis.

Application

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Product Information

• Catalog No.: HY-130703
• CAS No.: 23582-83-4
• Molecular Formula: C28H44O
• Molecular Weight: 396.65
• Purity: 91.96%
• Storage: -20°C, protect from light, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
• Availability: In-stock

Source

Original product source