Remisporine B is a polyketide, that can be isolated from Penicillium sp. ZJ-SY2. Remisporine B exhibits immunosuppressive efficacy, that inhibits concanavalin A ( HY-P2149 )-induced T-cell proliferation and LPS ( HY-D1056 )- induced B-cell proliferations of mouse splenic lymphocytes with IC 50 of 30.1 µg/mL and 32.4 µg/mL.
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