yGsy2p-IN-1 is a potent inhibitor for yeast glycogen synthase 2 (yGsy2p) . yGsy2p-IN-1 is a competitive human glycogen synthase 1 (hGYS1) inhibitor with an IC 50 of 2.75 μM and a K i of 1.31 μM for wild-type hGYS1. yGsy2p-IN-H23 a pyrazole inhibitor, is used for glycogen storage diseases (GSDs).
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