PROTAC BRD4 Degrader-6

Overview

PROTAC BRD4 Degrader-6 (compound 32a) is a potent small-molecule BRD4 PROTAC degrader with IC 50 value of 2.7 nM for BRD4 BD1. PROTAC BRD4 Degrader-6 potently degrades BRD4 protein and inhibits the expression of c-Myc . PROTAC BRD4 Degrader-6 inhibits the proliferation of pancreatic cancer cell line BxPC3 and induces apoptosis . PROTAC BRD4 Degrader-6 can be used for human pancreatic cancer research. (Pink: BRD4 ligand ( HY-100015 ); Blue: Cereblon ligand ( HY-A0003 ); Black: linker ( HY-108369 )).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Caspase | Products > Signaling Pathways > Epigenetic Reader Domain | Products > Signaling Pathways > c-Myc

Product Information

• Catalog No.: HY-131203
• CAS No.: 2410947-56-5
• Molecular Formula: C43H40F2N10O10S
• Molecular Weight: 926.90
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source