Desmorpholinyl Quizartinib-PEG2-COOH

Overview

Desmorpholinyl Quizartinib-PEG2-COOH incorporates a ligand for FLT-3 , and a PEG-based PROTAC linker. Desmorpholinyl Quizartinib-PEG2-COOH can be used in the synthesis of PROTAC FLT-3 degrader 1 ( HY-114323 ). PROTAC FLT-3 degrader 1 is a PROTAC FLT-3 internal tandem duplication (ITD) degrader with an IC 50 0.6 nM.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > Target Protein Ligand-Linker Conjugates

Product Information

• Catalog No.: HY-131230
• CAS No.: 2292116-14-2
• Molecular Formula: C30H33N5O7S
• Molecular Weight: 607.68
• Purity: 96.32%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source