8-Oxo-GTP

Overview

8-Oxo-GTP is an oxidized guanine nucleotide, produced by reactive oxygen species ( ROS ). 8-Oxo-GTP serves as a substrate for MutT protein, GTP cyclohydrolase II , Mycobacterium tuberculosis MutT1, and Mycobacterium tuberculosis Rv1700 , which hydrolyze it to corresponding nucleoside monophosphates or diphosphates. 8-Oxo-GTP causes detrimental effects including mutations and mistranslation when incorporated into nucleic acids. 8-Oxo-GTP can be used for the research of cancer and tuberculosis.

Application

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Product Information

• Catalog No.: HY-131597
• CAS No.: 21238-36-8
• Molecular Formula: C10H16N5O15P3
• Molecular Weight: 539.18
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source