TPC2-A1-N

Overview

TPC2-A1-N is a powerful and Ca 2+ -permeable agonist of two pore channel 2 (TPC2) , which plays its role by mimicking the physiological actions of NAADP. TPC2-A1-P reproducibly evokes significant Ca 2+ responses from TPC2 ( EC 50 =7.8 μM ), and the effect can be blocked by several TPC blockers. TPC2-A1-N can be used to probe different functions of TPC2 channels in intact cells.

Application

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Product Information

• Catalog No.: HY-131614
• CAS No.: 136186-07-7
• Molecular Formula: C17H9Cl2F3N2O2
• Molecular Weight: 401.17
• Purity: 99.86%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.08 mg/mL (5.18 mM); Clear solution
• Availability: In-stock

Source

Original product source