Pregnenolone 16α-carbonitrile

Overview

Pregnenolone 16α-carbonitrile is an orally active prototypical and effective rodent-PXR activator. Pregnenolone 16α-carbonitrile, a synthetic steroid, induces cytochrome P450 3A expression. Pregnenolone 16α-carbonitrile exhibits increased resistance to subsequent stressful insults.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Vitamin D Related/Nuclear Receptor | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Pregnane X Receptor (PXR) | Products > Signaling Pathways > Cytochrome P450

Product Information

• Catalog No.: HY-131723
• CAS No.: 1434-54-4
• Molecular Formula: C22H31NO2
• Molecular Weight: 341.49
• Purity: 98.42%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 1.43 mg/mL (4.19 mM); Clear solution
• Availability: In-stock

Source

Original product source