3-Chlorodiphenylamine

3-Chlorodiphenylamine
  • CAS No.:101-17-7
  • Grade:98.74%
  • Formula:C12H10ClN
  • M.W.:203.67
  • Solvent:≥ 5 mg/mL (24.55 mM); Clear solution

Overview

3-Chlorodiphenylamine is a high affinity Ca 2+ sensitizer of cardiac muscle. 3-Chlorodiphenylamine is based on diphenylamine and binds to the isolated N-domain of cardiac troponin C (cTnC) ( K d =6 µM ). 3-Chlorodiphenylamine is an excellent starting scaffold for the development of more potent Ca 2+ -sensitizing compounds due to its small size, and can be used for systolic heart failure research.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Cardiovascular Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Potassium Channel

Product Information

  • Catalog No.: HY-131948
  • CAS No.: 101-17-7
  • Molecular Formula: C12H10ClN
  • Molecular Weight: 203.67
  • Purity: 98.74%
  • Storage: Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
  • Solubility: ≥ 5 mg/mL (24.55 mM); Clear solution
  • Availability: In-stock

Source

Original product source


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