2'MeO6MF is a brain-penetrant positive allosteric modulator at α2β1γ2L and all α1 -containing GABA A receptors . 2'MeO6MF also can directly activate α2β2/3 and α2β2/3γ2L GABA A receptors . 2'MeO6MF has anxiolytic and psychomotor stabilizing properties. 2'MeO6MF offers neuroprotection and improved functional recovery and dampens the stroke-induced inflammatory response.
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