TDI-10229

Overview

TDI-10229 is a potent and orally bioavailable inhibitor of soluble adenylyl cyclase (sAC, ADCY10) . TDI-10229 displays nanomolar inhibition of sAC in both biochemical and cellular assays ( IC 50 of 195 nM) and exhibits mouse pharmacokinetic properties sufficient to warrant its use as an in vivo tool compound.

Application

Products | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Others | Products > Signaling Pathways > Adenylate Cyclase

Product Information

• Catalog No.: HY-132298
• CAS No.: 2810887-45-5
• Molecular Formula: C16H16ClN5
• Molecular Weight: 313.78
• Purity: 99.00%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.08 mg/mL (6.63 mM); Clear solution
• Availability: In-stock

Source

Original product source