CC-90005

Overview

CC-90005 is a potent, selective and orally active inhibitor of protein kinase C-θ (PKC-θ) , with an IC 50 of 8 nM. CC-90005 shows selectivity for PKC-θ over PKC-δ (IC 50 =4440 nM). CC-90005 can inhibit T cell activation by inhibiting IL-2 expression.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > TGF-beta/Smad | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > PKC

Product Information

• Catalog No.: HY-132304
• CAS No.: 1799574-70-1
• Molecular Formula: C21H27F2N7O2
• Molecular Weight: 447.48
• Purity: 99.11%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 1.25 mg/mL (2.79 mM); Clear solution
• Availability: In-stock

Source

Original product source