CCF0058981 (CCF981), 3-chlorophenyl analogue, is a noncovalent SARS-CoV-2 3CL pro (SC2) inhibitor with an IC 50 of 68 nM. CCF0058981 inhibits SC1 (SARS-CoV-1 3CL pro ) with an IC 50 of 19 nM. CCF0058981 has antiviral efficacy and has the potential for COVID-19 research.
Products | Products > Disease Areas > Infection | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > SARS-CoV | Products > Signaling Pathways > Virus Protease
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