ITK antagonist (compound 10 n) is a potent, orally active and selective ITK (Interleukin-2 inducible T-cell kinase) antagonist ( IC 50 =1 and 20 nM in different assays). ITK antagonist inhibits insulin receptor kinase (IRK) with an IC 50 of 160 nM.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Itk
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