Talabostat mesylate

Overview

Talabostat mesylate (Val-boroPro mesylate; PT100 mesylate) is an orally active and nonselective dipeptidyl peptidase IV (DPP-IV) inhibitor ( IC 50 < 4 nM; K i = 0.18 nM) and the inhibitor of fibroblast activation protein ( FAP ) ( IC 50 = 560 nM), inhibits DPP8/9 ( IC 50 = 4/11 nM; K i = 1.5/0.76 nM), quiescent cell proline dipeptidase (QPP) ( IC 50 = 310 nM), DPP2, and some other DASH family enzymes . Antineoplastic and hematopoiesis- stimulating activities.

Application

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Product Information

• Catalog No.: HY-13233A
• CAS No.: 150080-09-4
• Molecular Formula: C10H23BN2O6S
• Molecular Weight: 310.18
• Purity: 98.35%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2.5 mg/mL (8.06 mM); Clear solution
• Availability: In-stock

Source

Original product source