Dolutegravir (Standard)

Overview

Dolutegravir (Standard) is the analytical standard of Dolutegravir. This product is intended for research and analytical applications. Dolutegravir (S/GSK1349572) is a highly potent and orally bioavailable HIV integrase strand transfer inhibitor with an IC 50 of 2.7 nM for HIV-1 integrase-catalyzed strand transfer. Dolutegravir (S/GSK1349572) inhibits HIV-1 viral replication with an IC 50 of 0.51 nM in peripheral blood mononuclear cells. Dolutegravir retains a high potency against the HIV-1 Y143R, N155H, and G140S/Q148H mutants (EC 50 =3.6-5.8 nM).

Application

Products | Products > Disease Areas > Infection | Products > Signaling Pathways > Others | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > HIV Integrase | Products > Signaling Pathways > HIV

Product Information

• Catalog No.: HY-13238R
• CAS No.: 1051375-16-6
• Molecular Formula: C20H19F2N3O5
• Molecular Weight: 419.38
• Purity: 99.01%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source