Viltolarsen

Overview

Viltolarsen (NS-065/NCNP-01) is a phosphorodiamidate morpholino antisense oligonucleotide. Viltolarsen binds to exon 53 of the dystrophin mRNA precursor and restores the amino acid open-reading frame by skipping exon 53, resulting in the production of a shortened dystrophin protein that contains essential functional portions. Viltolarsen has the potential for Duchenne muscular dystrophy (DMD) research.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Cytoskeleton | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Nucleoside Antimetabolite/Analog | Products > Signaling Pathways > Dystrophin

Product Information

• Catalog No.: HY-132586
• CAS No.: 2055732-84-6
• Molecular Formula: C244H381N113O88P20
• Molecular Weight: 6924.82
• Purity: 95.25%
• Storage: -20°C, stored under nitrogen, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
• Solubility: 50 mg/mL (7.22 mM); Clear solution; Need ultrasonic
• Availability: In-stock

Source

Original product source