Sunvozertinib

Overview

Sunvozertinib (DZD9008) is a potent ErbBs ( EGFR , Her2, especially mutant forms) and BTK inhibitor. Sunvozertinib shows IC 50 s of 20.4, 20.4, 1.1, 7.5, and 80.4 nM for EGFR exon 20 NPH insertion, EGFR exon 20 ASV insertion, EGFR L858R and T790M mutations, and Her2 Exon20 YVMA, and EGFR WT A431, respectively (patent WO2019149164A1, example 52).

Application

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Product Information

• Catalog No.: HY-132842
• CAS No.: 2370013-12-8
• Molecular Formula: C29H35ClFN7O3
• Molecular Weight: 584.08
• Purity: 99.62%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (4.28 mM); Clear solution
• Availability: In-stock

Source

Original product source