Nepicastat hydrochloride

Overview

Nepicastat hydrochloride (SYN-117 hydrochloride) is a selective, potent, and orally active inhibitor of dopamine-beta-hydroxylase . Nepicastat hydrochloride produces concentration-dependent inhibition of bovine ( IC 50 =8.5 nM) and human ( IC 50 =9 nM) dopamine-beta-hydroxylase. Nepicastat hydrochloride can cross the blood-brain barrier (BBB).

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Cardiovascular Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Dopamine β-hydroxylase

Product Information

• Catalog No.: HY-13289A
• CAS No.: 170151-24-3
• Molecular Formula: C14H16ClF2N3S
• Molecular Weight: 331.81
• Purity: 99.40%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 0.6 mg/mL (1.81 mM); Clear solution
• Availability: In-stock

Source

Original product source