Resolvin E2

Overview

Resolvin E2 ((-)-Resolvin E2) is an endogenous lipid mediator produced from eicosapentaenoic acid (EPA) under the catalysis of 5-lipoxygenase ( 5-LOX ), and its production increases in hypoxic environments. Resolvin E2 antagonizes BLT1 , partially activates ChemR23 , and promotes ubiquitin-proteasome-mediated degradation of COX-2 . Resolvin E2 reduces the production of prostaglandin E 2 , blocks polymorphonuclear leukocyte infiltration, and promotes the resolution of airway inflammation. Resolvin E2 ameliorates lipopolysaccharide (LPS) ( HY-D1056 )-induced depressive-like behaviors . Resolvin E2 can be used in research related to depression, murine peritonitis, neonatal asthma, and other conditions.

Application

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Product Information

• Catalog No.: HY-133159
• CAS No.: 865532-70-3
• Molecular Formula: C20H30O4
• Molecular Weight: 334.45
• Purity: 98.5%
• Storage: Solution, -20°C, 2 years
• Availability: In-stock

Source

Original product source