Alkyne-Val-Cit-PAB-OH

Overview

Alkyne-Val-Cit-PAB is a cleavable ADC linker. The Val-Cit is effectively cleaved by lysosomal proteolytic enzymes while being highly stable in human plasma, making this a potent strategy in ADC linker design. The propargyl group can be linked to azide-containing biomolecules via Click Chemistry.

Application

Products > PEG Linkers > GGFG Linkers | Products > ADC Linker, ADC Payload > Cleavable Linkers > Val-Cit

Product Information

• Catalog No.: BP-26339
• CAS No.: 2748039-76-9
• Molecular Formula: C24H35N5O5
• Molecular Weight: 473.6
• Purity: 98%
• Storage: -20°C
• Availability: In Stock

Source

Original product source