Tos-PEG6-acid is a PEG linker containing a tosyl group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. HATU) to form a stable amide bond.
PEGylation of Protein, Peptide & Oligo > Amine Reactive > PEG Tosylate | Antibody Drug Conjugates > Amine Reactive > PEG Tosylate | Drug Delivery, Surface Modification > Amine Reactive > PEG Tosylate | Products > PEG Linkers > PEG Tosylate | Products > PEG Linkers > PEG Tosylate > Tos-PEG-acid
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