Varespladib -d 7 (LY315920-d 7 ) is a deuterated labeled Varespladib ( HY-13402 ). Varespladib is a potent and selective group IIA, secretory phospholipase A2 (sPLA2) inhibitor with an IC 50 of 9 nM. Varespladib exhibits the significant inhibitory effect on sPLA2 activity in serum from various species including rat, rabbit, guinea pig and human with IC 50 s of 8.1 nM, 5.0 nM, 3.2 nM and 6.2 nM, respectively.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Others | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Isotope-Labeled Compounds | Products > Signaling Pathways > Phospholipase
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