AUTAC1

Overview

AUTAC1 is a MetAP2 -targeting autophagy-mediated degrader ( AUTAC ). AUTACs contain a degradation tag and a warhead to provide target specificity. AUTAC1 contains an FBnG (p-Fluorobenzyl Guanine) and a Fumagillol moiety. Fumagillol binds covalently to MetAP2.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Autophagy | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Metabolic Disease | Products > Research Areas > Cancer | Products > Signaling Pathways > AUTACs | Products > Signaling Pathways > Autophagy

Product Information

• Catalog No.: HY-134183
• CAS No.: 2241669-09-8
• Molecular Formula: C44H63FN8O11S
• Molecular Weight: 931.08
• Purity: 95.0%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: 2.5 mg/mL (2.69 mM); Clear solution; Need ultrasonic
• Availability: In-stock

Source

Original product source