Z-Pro-Pro-CHO

Overview

Z-Pro-Pro-CHO is a potent inhibitor of prolyl oligopeptidase ( POP ), with extremely high affinity for human prolyl oligopeptidase ( HsPOP ) ( IC 50 =0.012 μM), and it also effectively inhibits the activity of Schistosoma mansoni prolyl oligopeptidase ( SmPOP ) ( IC 50 =0.16 μM). Z-Pro-Pro-CHO does not block the phosphorylation of ERK or the production of TNF-α or IFN-γ in immune cells from presensitized mice, nor does it induce harmful phenotypes in cultured Schistosoma mansoni schistosomula. Z-Pro-Pro-CHO only partially inhibits epithelial cell wound healing at extremely high concentrations. Z-Pro-Pro-CHO finds wide application in studies related to schistosomiasis.

Application

Products | Products > Peptides | Products > Disease Areas > Infection | Products > Disease Areas > Parasitic Infection | Products > Disease Areas > Schistosoma Japonicum Infection | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Prolyl Endopeptidase (PREP) | Products > Signaling Pathways > Parasite

Product Information

• Catalog No.: HY-134454
• CAS No.: 108708-25-4
• Molecular Formula: C18H22N2O4
• Molecular Weight: 330.38
• Purity: 98.03%
• Storage: Sealed storage, away from moisture. Powder -80°C, 2 years , -20°C, 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Availability: In-stock

Source

Original product source