BP Lipid 228 is an ionizable lipid. The dimethylamine lipid head enhances encapsulation of mRNA. The lipid has a C5 amide connection and two primary esters at C8 position relative to the amide nitrogen. The primary lipid tail has a mixture of 4 and 6 carbon tails. The lipid can be used for mRNA-based therapies which depends on the availability of a safe and efficient delivery vehicle. The pKa is 6.5.
PEGylation of Protein, Peptide & Oligo > Lipid Molecules > Ionizable Lipid | Drug Delivery, Surface Modification > Lipid Molecules > Ionizable Lipid | Products > Lipids In Drug Delivery > Ionizable Lipid | Products > Lipids In Drug Delivery > Ionizable Lipid > Lipid A9 & Analogs
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