CaV1.3 antagonist-1 is a potent and highly selective Ca V 1.3 L-type calcium channel (LTCC) antagonist with an IC 50 of 1.7 μM. CaV1.3 antagonist-1 inhibits Ca V 1.3 LTCC >600-fold more potently than Ca V 1.2 LTCC. CaV1.3 antagonist-1, a cyclopentyl derivative, has the potential for Parkinson's disease research .
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