(1R,2R)-ML-SI3

Overview

(1R,2R)-ML-SI3 is an isomer of ML-SI3 and a potent inhibitor of three isoforms of TRPML . (1R,2R)-ML-SI3 inhibits TRPMLs with IC 50 s of 1.6 μM (TRPML1), 2.3 μM (TRPML2), and 12.5 μM (TRPML3), respectively.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Pain | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > TRP Channel

Product Information

• Catalog No.: HY-134819A
• CAS No.: 2418594-00-8
• Molecular Formula: C23H31N3O3S
• Molecular Weight: 429.58
• Purity: 99.79%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 2.5 mg/mL (5.82 mM); Clear solution
• Availability: In-stock

Source

Original product source