HG-10-102-01

Overview

HG-10-102-01 is a highly potent, selective, and brain-penetrable LRRK2 inhibitor, with IC 50 values of 20.3 and 3.2 nM against wild-type LRRK2 and LRRK2[G2019S] , respectively. HG-10-102-01 also inhibits MNK2 and MLK1 , with IC 50 values of 0.6 and 2.1 μM. HG-10-102-01 can be used for Parkinson's disease (PD) research.

Application

Products | Products > Disease Areas > Parkinson's Disease | Products > Disease Areas > Obesity | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Lipid Metabolism | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > LRRK2 | Products > Signaling Pathways > MNK

Product Information

• Catalog No.: HY-13488
• CAS No.: 1351758-81-0
• Molecular Formula: C17H20ClN5O3
• Molecular Weight: 377.83
• Purity: 99.55%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2 mg/mL (5.29 mM); Clear solution
• Availability: In-stock

Source

Original product source