Totrombopag choline

Overview

Totrombopag (SB-559448) choline is an orally effective thrombopoietin receptor ( TpoR ) agonist. By activating TpoR , Totrombopag choline initiates an intracellular signaling cascade mediated by JAK2 kinase and the transcription factor Stat5 , a signaling process that is the primary mechanism regulating megakaryocyte growth and differentiation into platelets. Totrombopag choline can be used to study platelet production and megakaryocyte biology.

Application

Products | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Others | Products > Signaling Pathways > Thrombopoietin Receptor

Product Information

• Catalog No.: HY-135041
• CAS No.: 851606-62-7
• Molecular Formula: C30H35N9O3
• Molecular Weight: 569.66
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source