N-(4-acetamidophenyl)-Indomethacin amide

Overview

N-(4-acetamidophenyl)-indomethacin amide (N-4-AIA) is one of several aromatic amides of indomethacin reported to be potent and selective reversible inhibitors of COX-2 .1 N-4-AIA inhibits human recombinant and ovine COX-2 with IC 50 values of 0.12 and 0.625 μM, respectively. It is about 400 times less potent as an inhibitor of human recombinant COX-1 and 80 times less potent as an inhibitor of ovine COX-1 than ovine COX-2 .

Application

Products | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Others | Products > Signaling Pathways > COX

Product Information

• Catalog No.: HY-135081
• CAS No.: 261766-23-8
• Molecular Formula: C27H24ClN3O4
• Molecular Weight: 489.95
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source