CCG-50014

Overview

CCG-50014 is the most potent against the regulator of G-protein signaling protein type 4 ( RGS4 ) ( IC 50 =30 nM) and is >20-fold selective for RGS4 over other RGS proteins. CCG-50014 binds covalently to the RGS, forming an adduct on two cysteine residues located in an allosteric regulatory site. CCG50014, reduces nociceptive responses and enhances opioid-mediated analgesic effects in the mouse formalin test.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > RGS Protein

Product Information

• Catalog No.: HY-13509
• CAS No.: 883050-24-6
• Molecular Formula: C16H13FN2O2S
• Molecular Weight: 316.35
• Purity: 99.62%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Availability: In-stock

Source

Original product source