Globalagliatin

Overview

Globalagliatin (LY2608204) is an orally active glucokinase ( GK ) activator with an EC 50 of 42 nM. Globalagliatin also stimulates glucose metabolism in rat insulinoma INS1-E cells with an EC 50 of 579 nM. Globalagliatin targets both pancreatic β-cells and hepatocytes. Globalagliatin is promising for research of type 2 diabetes.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Glucose Metabolism | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Glucokinase

Product Information

• Catalog No.: HY-13529
• CAS No.: 1234703-40-2
• Molecular Formula: C28H37N3O3S3
• Molecular Weight: 559.81
• Purity: 99.45%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (4.47 mM); Clear solution
• Availability: In-stock

Source

Original product source