t-Boc-N-amido-PEG4-Val-Cit

Overview

t-Boc-N-amido-PEG4-Val-Cit is a protease-cleavable ADC linker featuring a Boc-protected amine, a hydrophilic PEG spacer, and a Val-Cit dipeptide. The Val-Cit dipeptide is cleavable by cell proteases and features a carboxylic acid which is free for coupling reactions with amines to form amides. The Boc can be removed under acidic conditions to reveal a free primary amine, which may be used in a variety of reactions such as coupling or reductive amination.

Application

Products > PEG Linkers > GGFG Linkers | Products > ADC Linker, ADC Payload > Cleavable Linkers > Val-Cit

Product Information

• Catalog No.: BP-40279
• CAS No.: 2231240-82-5
• Molecular Formula: C27H51N5O11
• Molecular Weight: 621.7
• Purity: 95%
• Storage: -20°C
• Availability: In Stock

Source

Original product source