Nifurpirinol (Standard)

Overview

Nifurpirinol (P-7138) (Standard) is the analytical standard of Nifurpirinol ( HY-135470 ). This product is intended for research and analytical applications. Nifurpirinol (P-7138) is a selective prosubstrate of bacterial nitroreductase (NTR) . NTR catalyzes the reduction of nifurpirinol to generate cytotoxic metabolites that induce apoptosis in target cells. Nifurpirinol selectively ablates NTR-expressing cells such as pancreatic β cells, osteoblasts, dopaminergic neurons, and podocytes in transgenic zebrafish models. Nifurpirinol can be used in regeneration studies and disease modeling such as focal segmental glomerulosclerosis (FSGS).

Application

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Product Information

• Catalog No.: HY-135470R
• CAS No.: 13411-16-0
• Molecular Formula: C12H10N2O4
• Molecular Weight: 246.22
• Purity: 95%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source