5-Carboxamidotryptamine (5-CT) is a 5-HT 1A , 5-HT 1B , 5-HT 1D , 5-HT 5A , 5-HT 7 receptor agonist. 5-Carboxamidotryptamine has a K i value of 4.6 nM for cloned human 5-HT 5A receptor. 5-Carboxamidotryptamine causes a dose-dependent reduction in rectal temperature of mice.
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