Norfluoxetine oxalate

Overview

Norfluoxetine oxalate is the active metabolite of the antidepressant Fluoxetine ( HY-B0102 ); it is also a TREK-2 K 2 P potassium channel inhibitor . Norfluoxetine oxalate exhibits neuroimmunological activity, induces apoptosis in primary microglial cells, and inhibits the release of pro-inflammatory factors. Norfluoxetine oxalate inhibits high-threshold voltage-gated Ca 2+ currents in neurons with an EC 50 of 20.4 μM. Norfluoxetine oxalate can be used in research related to depression, ischemic stroke, and epilepsy.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Cerebrovascular Disease | Products > Disease Areas > Depression | Products > Disease Areas > Epilepsy | Products > Disease Areas > Ischemic Stroke | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Neurological Disease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Drug Metabolite | Products > Signaling Pathways > Potassium Channel | Products > Signaling Pathways > Calcium Channel | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-135556A
• CAS No.: 107674-50-0
• Molecular Formula: C18H18F3NO5
• Molecular Weight: 385.33
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source