RK-682 hemicalcium

Overview

RK-682 hemicalcium is the hemicalcium salt form of RK-682 ( HY-135564A ). RK-682 hemicalcium is the inhibitor for protein tyrosine phosphatase ( PTPase ), heparanase , phospholipase A2 and HIV-1 protease . RK-682 hemicalcium inhibits the dephosphorylation of CD45 ( IC 50 is 54 μM) and VHR ( IC 50 is 2.0 μM), and thereby inhibits the ERK signaling pathway. RK-682 hemicalcium inhibits the cell viability of cancer cell MGH-U3, T24 and UROtsa with IC 50 s of 78.2, 43.2 and 145 nM, respectively, arrests the cell cycle at G1/S phase, inhibits the cell migration and autophagy in MGH-U3 and T24[2].

Application

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Product Information

• Catalog No.: HY-135564
• CAS No.: 332131-32-5
• Molecular Formula: C21H36O5.1/2Ca
• Molecular Weight: 408.59
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source