Methocinnamox

Overview

Methocinnamox (M-CAM) a selective and long-acting μ-opioid receptor ( MOR ) antagonist with a K i of 0.6 nM. Methocinnamox binds to the orthosteric site of the MOR in a pseudo-irreversible, non-covalent manner, resulting in prolonged receptor blockade that persists until new receptors are synthesized. Methocinnamox acts as a reversible antagonist at both the kappa-opioid receptor ( KOR ) ( K i = 4.9 nM) and delta-opioid receptor ( DOR ) ( K i = 2.2 nM), and it exhibits no intrinsic agonist activity at these receptors. Methocinnamox can be used to reverse and prevent opioid overdose and addiction.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Opioid Receptor

Product Information

• Catalog No.: HY-135698
• CAS No.: 117339-76-1
• Molecular Formula: C30H32N2O4
• Molecular Weight: 484.59
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source