TFEB activator 1 is an orally effective, mTOR-independent activator of TFEB . TFEB activator 1 significantly promotes the nuclear translocation of Flag-TFEB with an EC 50 of 2167 nM. TFEB activator 1 enhances autophagy without inhibiting the mTOR pathway and has the potential for neurodegenerative diseases treatment.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Autophagy | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Autophagy
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