SARS-CoV-IN-1 is an effective inhibitor of SARS-CoV replication. SARS-CoV-IN-1 shows anti-Coronavirus activity with an EC 50 of 4.9 μM in Vero cells. SARS-CoV-IN-1 inhibits the 3D7 and W2 strains of P. falciparum with IC 50 s of 15.4 and 133.2 nM; and IC 90 s of 25.7 and 459.1 nM; respectively. Antimalarial and antiviral activities.
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