(S,R,S)-AHPC-C5-COOH

Overview

(S,R,S)-AHPC-C5-COOH (VH032-C5-COOH) is a synthesized E3 ligase ligand-linker conjugate , contains the VH032 VHL-based ligand and a linker to form PROTAC s. VH-032 is a selective and potent inhibitor of VHL/HIF-1α interaction with a K d of 185 nM, has the potential for the study of anemia and ischemic diseases.

Application

Products | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > E3 Ligase Ligand-Linker Conjugates | Products > Signaling Pathways > HIF/HIF Prolyl-Hydroxylase

Product Information

• Catalog No.: HY-136055
• CAS No.: 2267282-19-7
• Molecular Formula: C29H42N4O5S
• Molecular Weight: 558.73
• Purity: 98.81%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: 2.5 mg/mL (4.47 mM); Clear solution; Need ultrasonic
• Availability: In-stock

Source

Original product source