iFSP1

Overview

iFSP1 is a potent, selective and glutathione-independent inhibitor of ferroptosis suppressor protein 1 (FSP1) (AIFM2) with an EC 50 of 103 nM. iFSP1 selectively induces ferroptosis in GPX4-knockout cells which overexpressed FSP1. iFSP1 is able to sensitize a variety of human cancer cell lines to the ferroptosis inducer, such as (1S,3R)-RSL3 ( HY-100218A ).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > PROTAC | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Signaling Pathways > Ferroptosis | Products > Signaling Pathways > Ligands for Target Protein for PROTAC

Product Information

• Catalog No.: HY-136057
• CAS No.: 150651-39-1
• Molecular Formula: C20H13N5
• Molecular Weight: 323.35
• Purity: 99.96%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: 2 mg/mL (6.19 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source