SIRT1-IN-1 is a selective SIRT1 inhibitor with an IC 50 of 0.205 μM. SIRT1-IN-1 inhibits SIRT2 with an IC 50 of 11.5 μM. SIRT1-IN-1, a indole, is a cytomegalovirus ( CMV ) inhibitors and has antiviral activity.
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