BSJ-03-204

Overview

BSJ-03-204 is a PROTAC linking a Cereblon ligand to a CDK ligand, serving as a potent and selective dual degrader of CDK4/6 . BSJ-03-204 exhibits IC 50 values of 26.9 nM and 10.4 nM against CDK4/D1 and CDK6/D1, respectively. BSJ-03-204 can be utilized for cancer-related research. (Pink: Cdk4/cyclin D1 and Cdk6/cyclin D2 ligand ( HY-50767 ); Blue: Cereblon ligand ( HY-103596 ); Black: linker ( HY-W007803 )).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > CDK

Product Information

• Catalog No.: HY-136250
• CAS No.: 2349356-09-6
• Molecular Formula: C43H48N10O8
• Molecular Weight: 832.90
• Purity: 99.76%
• Storage: -20°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 2.5 mg/mL (3.00 mM); Clear solution
• Availability: In-stock

Source

Original product source