BAY-876 (Standard)

Overview

BAY-876 (Standard) is the analytical standard of BAY-876 ( HY-100017 ). This product is intended for research and analytical applications. BAY-876 , a chemical probe, is an orally active and selective glucose transporter 1 ( GLUT1 ) inhibitor with an IC50 of 2 nM. BAY-876 is >130-fold more selective for GLUT1 than GLUT2 , GLUT3 , and GLUT4 . BAY-876 is also a potent blocker of glycolytic metabolism and ovarian cancer growth. In addition, BAY-876 can induce the formation of disulfide bonds in actin cytoskeletal proteins, leading to the occurrence of cellular disulfidptosis .

Application

Products | Products > Signaling Pathways > Others | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > GLUT | Products > Signaling Pathways > Disulfidptosis

Product Information

• Catalog No.: HY-100017R
• CAS No.: 1799753-84-6
• Molecular Formula: C24H16F4N6O2
• Molecular Weight: 496.42
• Purity: 95%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source