Encequidar hydrochloride

Overview

Encequidar hydrochloride (HM30181 hydrochloride) is an oral P-glycoprotein (P-gp) inhibitor with the activity of enhancing the oral bioavailability of P-gp substrate drugs. Encequidar shows the highest potency among various MDR1 inhibitors, with IC 50 =0.63nM. Encequidar effectively blocks the transepithelial transport of paclitaxel in MDCK monolayer cells, with IC 50 =35.4nM.

Application

Products | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Others | Products > Signaling Pathways > P-glycoprotein

Product Information

• Catalog No.: HY-13646B
• CAS No.: 849675-88-3
• Molecular Formula: C38H37ClN6O7
• Molecular Weight: 725.19
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source