RP101075

Overview

RP101075, an active metabolite of Ozanimod, is a potent, orally active S1PR (sphingosine-1-phosphate receptor 1) agonist, with an EC 50 of 0.27 nM. RP101075 displays >100-fold selectivity over S1PR5 (EC 50 =5.9 nM) and >10000-fold over S1PR 2, 3, and 4. RP101075 displays superior cardiovascular safety profile.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > LPL Receptor | Products > Signaling Pathways > Drug Metabolite

Product Information

• Catalog No.: HY-136576
• CAS No.: 1306760-73-5
• Molecular Formula: C21H20N4O2
• Molecular Weight: 360.41
• Purity: 99.19%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 5 mg/mL (13.87 mM); Clear solution
• Availability: In-stock

Source

Original product source