NPD-001

NPD-001
  • CAS No.:469863-16-9
  • Grade:98.11%
  • Formula:C33H40N6O4
  • M.W.:584.72

Overview

NPD-001 is a potent Trypanosoma brucei phosphodiesterases 1/2 ( TbrPDEB1/2 ) inhibitor, with IC 50 values of 4 and 3 nM, respectively. NPD-001 also inhibits hPDE4. NPD-001 can increase cAMP levels in parasites, prevent cytokinesis, and cause the parasites to form multinucleated, multi-flagellated cells that eventually lyse. NPD-001 can be used for the research of infection .

Application

Products | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Colorectal Cancer | Products > Disease Areas > Digestive System Cancer | Products > Disease Areas > Parasitic Infection | Products > Disease Areas > Depression | Products > Disease Areas > Alzheimer's Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Infection | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Digestive System Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Phosphodiesterase (PDE) | Products > Signaling Pathways > Parasite

Product Information

  • Catalog No.: HY-136637
  • CAS No.: 469863-16-9
  • Molecular Formula: C33H40N6O4
  • Molecular Weight: 584.72
  • Purity: 98.11%
  • Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
  • Availability: In-stock

Source

Original product source


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